UNCONJUGATED
The Unconjugated Bilirubin test measures the level of indirect bilirubin in the blood. This form of bilirubin is produced from the breakdown of red blood cells and travels to the liver, where it is converted into conjugated (direct) bilirubin for elimination from the body. This test helps evaluate the early stage of bilirubin metabolism.
Elevated unconjugated bilirubin levels may occur due to increased breakdown of red blood cells (hemolysis), conditions like hemolytic anemia, or problems with liver uptake and processing, such as in Gilbert’s syndrome. It may lead to symptoms like jaundice, especially in newborns and in certain medical conditions. This test is usually interpreted along with total and conjugated bilirubin for accurate diagnosis.
The Unconjugated Bilirubin test is simple and requires a small blood sample. Accurate results help doctors identify the cause of jaundice, diagnose blood or liver disorders, and guide appropriate treatment.